Søren Dabelsteen Isior
M.D., PhD student (enrolled 2022)
soeisi@clin.au.dk
Department: Endocrinology, Aarhus University Hospital
Main supervisor: Søren Gregersen
Research Area
- Diabetic complications
- Pathophysiology and diabetes pharmacology
Research description
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Effect of increased insulin sensitivity on biochemical bone turnover markers and biomechanical bone properties in people with type 2 diabetes. I investigate how changes in insulin sensitivity following exercise affect biochemical bone turnover markers and biomechanical bone properties in people with type 2 diabetes. Type two diabetes increases the risk of bone fracture. However, decreased bone mineral density (BMD) does not sufficiently explain the increased fracture risk in type 2 diabetes and the risk is underestimated when using the standard risk assessment tools. To predict and prevent fractures caused by type 2 diabetes it is therefore important to understand the pathophysiology behind the increased risk of bone fracture.