Emma Börgeson, PhD, Docent
Associate professor
emma.borgeson@biomed.au.dk
+45 9352 2984
Research areas
- Inflammation
- Adipose tissue
- Obesity
- Cardiometabolic disease
- Cardiovascular disease
Research description
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My research focuses on understanding and modulating human immunology, with a specific focus on cardiometabolic disease mechanisms.
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Dysregulated chronic inflammation plays a crucial role in driving cardiometabolic disease. Inflammation consists of the initial acute phase, followed by a resolving phase. Importantly, the latter is regulated by specialized pro-resolving lipid mediators, e.g. the lipoxins, acting through defined receptors.
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Our work has demonstrated that promoting inflammatory resolution through the administration of lipoxins attenuates obesity-related experimental disease, and protects against cardiovascular events. Ongoing work now deciphers the molecular mechanisms involved, through the utilization of patient-specific ex vivo cell cultures and biobanked human material.