Project: Early Onset Type 2-Diabetes

An increasing number of young adults are being diagnosed with type 2 diabetes, and they are often affected more severely than older adults with the disease.

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New project investigates early onset type 2-diabetes

An increasing number of young adults are being diagnosed with type 2 diabetes, and they are often affected more severely than older adults with the disease. They live longer with the condition, experience more complications, and are impacted during a crucial life stage involving education, work, and family formation.

At the same time, we lack sufficient knowledge because young adults are rarely included in the clinical studies on which treatment guidelines are based.

We want to establish a new multidisciplinary research and innovation program working to identify and understand the biological, environmental, and social mechanisms driving disease burden, comorbidities, and reduced quality of life in individuals with EoT2D.

Overall, the objective is to generate new knowledge and to develop new solutions and models that can be implemented in diabetes care.

Work package output

The work packages described here (WP1–WP4) deliver complementary outputs that together form the foundation for the programme’s overall impact.

This WP lays the scientific foundation for understanding to what degree and in which areas the younger population is worse off than the older population with T2D and combined with studying their treatment, health seeking and risk behaviour, we can document whether we can detect people with EoT2D at an earlier stage and initiate treatment earlier and more intensively.

Furthermore, documenting health literacy and the self-management abilities among the young population with T2D lays the scientific foundation for WP4 to develop initiatives targeted this population.

WP leader

Anette Andersen
Read about Anette Andersen (DA)

This WP addresses a key unmet need: ensuring that young individuals with diabetes receive the correct diagnosis at the right time.

By bridging genetic, immunologic, and clinical data, the project lays the groundwork for improved diagnostic tools and evidence-based algorithms that can be implemented in routine care.

Ultimately, this will translate into earlier, safer, and more effective treatment for individuals living with early-onset diabetes in Denmark and beyond.

WP leader

Julie Støy
Read about Julie Støy

Examines the intersection between pregestational type 2 diabetes (T2D) and pregnancy by investigating the mechanisms behind insulin resistance, the long-term effects of pregnancies complicated by T2D, and women’s lived experiences of managing both pregnancy and diabetes.

This WP generates new scientific insights that can strengthen clinical practice and support women and their children across the life course.

WP leader

Ulla Kampmann Opstrup
Read about Ulla Kampmanm Opstrup

Generates insight into what everyday life looks for the target group and identifies patient needs and challenges in living with diabetes.

This comprehensive understanding lays the foundation for developing and testing new, innovative solutions together with patients, the healthcare system, and civil society. Solutions that are sustainable — and that can meaningfully improve the quality of life for people living with Eo2TD.

WP leader

Trine Laura Overgaard Hasle
Read about Trine Laura Overgaard Hasle (DA)

Contact

Annelli Sandbæk

anesnd@rm.dk
+45 2128 2073

Project: Early Onset Type 2-Diabetes

New project investigates early onset type 2-diabetes

Work package output

WP1 - Epidemiological studies

WP leader

WP2 - Geno- and phenotyping of EoT2D: Cancer Risk and Oral health perspectives

WP leader

WP3 - Pregnant women with T2D and their offspring

WP leader

WP4 - Differentiated initiative for people with EoT2D

WP leader

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